Female fecundability is associated with pre-pregnancy allostatic load: Analysis of a Chinese cohort.

ABSTRACT:

Introduction

Allostatic load (AL) is a practical index that reflects multi-system physiological changes which occur in response to chronic psychosocial stress. This study investigated the association between female pre-pregnancy allostatic load and time to pregnancy.

Material and methods

We enrolled 444 women who met the inclusion criteria and were attempting to achieve pregnancy. Their allostatic load scores at baseline were evaluated by nine indicators (systolic blood pressure, diastolic blood pressure, fasting plasma glucose, plasma cortisol, noradrenaline, interleukin-6, hypersensitive C-reactive protein, high density lipoprotein cholesterol and body mass index). The participants were followed up and their pregnancy outcome ascertained 1 year later; we then calculated ti

SUBMITTER: Hong X 

PROVIDER: S-EPMC9812113 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature