Clinical Assessment of Late Health Outcomes in Survivors of Wilms Tumor.

ABSTRACT:

Objectives

We aimed to clinically characterize the health, neurocognitive, and physical function outcomes of curative treatment of Wilms tumor.

Methods

Survivors of Wilms tumor (n = 280) participating in the St. Jude Lifetime Cohort, a retrospective study with prospective follow-up of individuals treated for childhood cancer at St. Jude Children's Research Hospital, were clinically evaluated and compared to age and sex-matched controls (n = 625). Health conditions were graded per a modified version of the National Cancer Institute's Common Terminology Criteria for Adverse Events. Standardized neurocognitive testing was graded by using age-adjusted z-scores. Impaired physical function was defined by age- and sex-matched z-scores >1.5 SD below controls. Modified Poisson reg

SUBMITTER: Foster KL 

PROVIDER: S-EPMC9812640 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature