Progress in precision therapy in pediatric oncology.

ABSTRACT:

Purpose of review

The fields of precision medicine and cancer genomics in pediatric oncology are rapidly evolving. Novel diagnostic tools are critical in refining cancer diagnoses, stratifying patient risk, and informing treatment decisions. This review is timely and relevant as it discusses advantages and drawbacks of common molecular profiling techniques and highlights novel platforms, which may address select limitations. We discuss recent publications demonstrating utility of large-scale molecular profiling and feasibility and logistics of matching targeted therapies to patients.

Recent findings

We describe the increased accessibility of next-generation sequencing, complementary profiling methods, and strategies to guide treatment decisions. We describe curation and shar

SUBMITTER: O'Donohue T 

PROVIDER: S-EPMC9812924 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature