Hepatic sarcoidosis with symptomatic portal hypertension: A report of 12 cases with review of the literature.

ABSTRACT:

Introduction

Sarcoidosis is a systemic granulomatosis of unknown etiology, characterized by the presence of immune granulomas. Liver damage is a relatively common extra-pulmonary manifestation, occurring in 3.6-30% of cases. Some patients can develop symptomatic portal hypertension (PH). Few series have evaluated the prognosis of symptomatic PH as well as the efficacy and safety of specific treatment on this complication.

Methods

This is a multicenter retrospective study of cases of histologically proven hepatic sarcoidosis with symptomatic PH (ascites, digestive hemorrhage) and/or hepatic encephalopathy. Demographic characteristics, comorbidities, clinical manifestations of sarcoidosis, biological data, imaging study of the liver, treatment, and clinical outcomes were colle

SUBMITTER: Fauter M 

PROVIDER: S-EPMC9812951 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature