Platelet abnormalities in autoimmune thyroid diseases: A systematic review and meta-analysis.

ABSTRACT:

Background

Some degree of platelet index abnormality has been found clinically in the autoimmune thyroid disease (AITD), but the findings are not uniform.

Methods

The PubMed, Web of Science, Cochrane Library, and Embase databases were searched for relevant articles published up to August 16th, 2022, with no restrictions on the language of the articles. Reference lists of eligible articles were also searched. A random effect model was used to pool the standardized mean difference (SMD) and 95% confidence interval (95% CI) of platelet count (PLT), mean platelet volume (MPV), and platelet distribution width (PDW) between AITD patients and healthy controls, and subgroup analyses were performed.

Results

A total of 19 articles with 6173 people (3824 AITD patients and 2349 h

SUBMITTER: Cao YT 

PROVIDER: S-EPMC9812954 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature