Cost-effectiveness of clinical breast examination screening programme among HER2-positive breast cancer patients: a modelling study.

ABSTRACT:

Purpose

For many low- and middle-income countries (LMICs), breast cancer (BC) screening based on mammography is not a viable option. Clinical breast examination (CBE) may represent a pragmatic and cost-effective alternative. This paper examines the cost-effectiveness of CBE screening programme among a patient group for whom its cost-effectiveness is likely to be least evident (HER2-positive patients) and discuss the wider implications for BC screening in LMICs.

Methods

A Markov model was used to examine clinical and economic outcomes over a life-time horizon from the patient, public payer, and healthcare sector perspective. HER2-positive patients entered the model at either disease-free survival or metastatic BC state. The downstaging effect of CBE determined the starting pr

SUBMITTER: Ngan TT 

PROVIDER: S-EPMC9813013 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature