Value of a web-based pediatric drug information system to prevent serious adverse drug reactions in child and adolescent psychiatry.

ABSTRACT: Psychotropic drugs are frequently prescribed 'off-label' to children and adolescents and carry the risk of serious adverse drug reactions (sADR). We examined the frequency of sADRs of psychotropic drugs in pediatric inpatients and explored their potential preventability through following the recommendations of a web-based pediatric drug information system (PDIS). The potential socio-economic impacts of using this online system is also addressed. Routine clinical data from all inpatients treated in a child and adolescent psychiatry department between January 2017 and December 2018 were retrospectively examined for the occurrence of sADRs as defined by the European Medicines Agency. The preventability of the sADRs was assessed based on the information of the PDIS. Furthermore, the expected p

SUBMITTER: Fekete S 

PROVIDER: S-EPMC9813149 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature