Role of Economic Evaluations on Pricing of Medicines Reimbursed by the Italian National Health Service.

ABSTRACT:

Objective

The main objective of this study was to explore the extent to which the incremental cost-effectiveness ratio (ICER), alongside other factors, predicts the final outcome of medicine price negotiation in Italy. The second objective was to depict the mean ICER of medicines obtained after negotiation.

Methods

Data were extracted from company dossiers submitted to the Italian Medicines Agency (AIFA) from October 2016 to January 2021 and AIFA's internal database. Beta-based regression analyses were used to test the effect of ICER and other variables on the outcome of price negotiation (ΔP), defined as the percentage difference between the list price requested by manufacturers and the final price paid by the Italian National Health Service (INHS).

Results

In our da

SUBMITTER: Russo P 

PROVIDER: S-EPMC9813158 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature