A century of exercise physiology: lung fluid balance during and following exercise.

ABSTRACT:

Purpose

This review recalls the principles developed over a century to describe trans-capillary fluid exchanges concerning in particular the lung during exercise, a specific condition where dyspnea is a leading symptom, the question being whether this symptom simply relates to fatigue or also implies some degree of lung edema.

Method

Data from experimental models of lung edema are recalled aiming to: (1) describe how extravascular lung water is strictly controlled by "safety factors" in physiological conditions, (2) consider how waning of "safety factors" inevitably leads to development of lung edema, (3) correlate data from experimental models with data from exercising humans.

Results

Exercise is a strong edemagenic condition as the increase in cardiac output leads t

SUBMITTER: Miserocchi G 

PROVIDER: S-EPMC9813172 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature