Deep Capillary Nonperfusion on OCT Angiography Predicts Complications in Eyes with Referable Nonproliferative Diabetic Retinopathy.

ABSTRACT:

Objective

To evaluate the ability of capillary nonperfusion parameters on OCT angiography (OCTA) to predict the development of clinically significant outcomes in eyes with referable nonproliferative diabetic retinopathy (NPDR).

Design

Prospective longitudinal observational study.

Subjects

In total, 59 patients (74 eyes) with treatment-naive moderate and severe (referable) NPDR.

Methods

Patients were imaged with OCTA at baseline and then followed-up for 1 year. We evaluated 2 OCTA capillary nonperfusion metrics, vessel density (VD) and geometric perfusion deficits (GPDs), in the superficial capillary plexus, middle capillary plexus (MCP), and deep capillary plexus (DCP). We compared the predictive accuracy of baseline OCTA metrics for clinically significant diab

SUBMITTER: Ong JX 

PROVIDER: S-EPMC9813273 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature