Liver injury on admission linked to worse outcomes in COVID-19: an analysis of 14,138 patients.

ABSTRACT:

Background

Infection with the SARS-CoV-2 virus, which can result in hepatic inflammation and injury that varies from mild to severe and potentially acute fulminant liver injury, may be associated with poor outcomes. Our aims were to: (I) assess baseline clinical and demographic characteristics in patients with coronavirus disease 2019 (COVID-19) who did and did not have abnormalities in liver chemistries [alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and total bilirubin (Tbili)] and (II) evaluate associations between abnormalities in liver chemistries and the primary outcomes of in-hospital death, intubation, and hospital length of stay (LOS).

Methods

In this nationwide retrospective cohort study of 14,138 patients, we analyzed

SUBMITTER: Chela HK 

PROVIDER: S-EPMC9813654 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature