Evolutionary reconstruction, nomenclature and functional meta-analysis of the Kiwellin protein family.

ABSTRACT: Crop diseases caused by pathogens critically affect global food security and plant ecology. Pathogens are well adapted to their host plants and have developed sophisticated mechanisms allowing successful colonization. Plants in turn have taken measures to counteract pathogen attacks resulting in an evolutionary arms race. Recent studies provided mechanistic insights into how two plant Kiwellin proteins from Zea mays mitigate the activity of the chorismate mutase Cmu1, a virulence factor secreted by the fungal pathogen Ustilago maydis during maize infection. Formerly identified as human allergens in kiwifruit, the biological function of Kiwellins is apparently linked to plant defense. We combined the analysis of proteome data with structural predictions to obtain a holistic ov

SUBMITTER: Klemm P 

PROVIDER: S-EPMC9813671 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature