Prognostic value of pan-immune-inflammation value in colorectal cancer patients: A systematic review and meta-analysis.

ABSTRACT:

Background

The pan-immune-inflammation value (PIV) has been reported as a novel prognostic biomarker in multiple malignancies. The aim of this study is to investigate the prognostic value of the PIV in patients with colorectal cancer.

Methods

We comprehensively searched electronic databases including PubMed, Embase and Web of Science up to August 2022. The endpoints were survival outcomes. Hazard ratios (HRs) with 95% confidence intervals (CIs) for survival data were collected for analysis.

Results

Six studies including 1879 participants were included. A significant heterogeneity in the PIV cut-off value among studies was observed. The combined results indicated that patients in the high baseline PIV group had a worse overall survival (HR=2.09; 95%CI: 1.67-2.61; P<0.0

SUBMITTER: Yang XC 

PROVIDER: S-EPMC9813847 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature