Putative adverse outcome pathways for silver nanoparticle toxicity on mammalian male reproductive system: a literature review.

ABSTRACT:

Background

Adverse outcome pathways (AOPs) are conceptual frameworks that organize knowledge about biological interactions and toxicity mechanisms. They present a sequence of events commencing with initial interaction(s) of a stressor, which defines the perturbation in a biological system (molecular initiating event, MIE), and a dependent series of key events (KEs), ending with an adverse outcome (AO). AOPs have recently become the subject of intense studies in a view to better understand the mechanisms of nanomaterial (NM) toxicity. Silver nanoparticles (Ag NPs) are one of the most explored nanostructures and are extensively used in various application. This, in turn, has increased the potential for interactions of Ag NPs with environments, and toxicity to human health. The aim of

SUBMITTER: Kose O 

PROVIDER: S-EPMC9814206 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature