A computationally efficient method for approximating reliabilities in large-scale single-step genomic prediction.

ABSTRACT:

Background

In this study, computationally efficient methods to approximate the reliabilities of genomic estimated breeding values (GEBV) in a single-step genomic prediction model including a residual polygenic (RPG) effect are described. In order to calculate the reliabilities of the genotyped animals, a single nucleotide polymorphism best linear unbiased prediction (SNPBLUP) or a genomic BLUP (GBLUP), was used, where two alternatives to account for the RPG effect were tested. In the direct approach, the genomic model included the RPG effect, while in the blended method, it did not but an index was used to weight the genomic and pedigree-based BLUP (PBLUP) reliabilities. In order to calculate the single-step GBLUP reliabilities for the breeding values for the non-genotyped animals,

SUBMITTER: Gao H 

PROVIDER: S-EPMC9814342 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature