Prognostic significance of pretreatment systemic immune-inflammation index in patients with prostate cancer: a meta-analysis.

ABSTRACT:

Background

The SII (systemic immune-inflammation index) has been extensively reported to have a prognostic value in prostate cancer (PCa), despite the unconformable results. The purpose of this meta-analysis is to quantify the effect of pretreatment SII on survival outcomes in patients with PCa.

Methods

The following databases were searched: Web of Science, Cochrane Library, PubMed, Embase, and China National Knowledge Infrastructure (CNKI). For exploration of the SII's correlations with the overall survival (OS) and the progression-free survival/biochemical recurrence-free survival (PFS/bRFS) in PCa, the pooled hazard ratios (HRs) were assessed within 95% confidence intervals (CIs).

Results

The present meta-analysis covered 10 studies with 8133 patients. Among the PC

SUBMITTER: Zhang B 

PROVIDER: S-EPMC9814343 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature