Cerebellar gray matter volume changes in patients with schizophrenia: A voxel-based meta-analysis.

ABSTRACT:

Background

In schizophrenia, the structural changes in the cerebellum are associated with patients' cognition and motor deficits. However, the findings are inconsistent owing to the heterogeneity in sample size, magnetic resonance imaging (MRI) scanners, and other factors among them. In this study, we conducted a meta-analysis to characterize the anatomical changes in cerebellar subfields in patients with schizophrenia.

Methods

Systematic research was conducted to identify studies that compare the gray matter volume (GMV) differences in the cerebellum between patients with schizophrenia and healthy controls with a voxel-based morphometry (VBM) method. A coordinate-based meta-analysis was adopted based on seed-based d mapping (SDM) software. An exploratory meta-regression ana

SUBMITTER: Li X 

PROVIDER: S-EPMC9814486 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature