Dual sequence definition increases the data storage capacity of sequence-defined macromolecules.

ABSTRACT: Sequence-defined macromolecules offer applications in the field of data storage. Challenges include synthesising precise and pure sequences, reading stored information and increasing data storage capacity. Herein, the synthesis of dual sequence-defined oligomers and their application for data storage is demonstrated. While applying the well-established Passerini three-component reaction, the degree of definition of the prepared monodisperse macromolecules is improved compared to previous reports by utilising nine specifically designed isocyanide monomers to introduce backbone definition. The monomers are combined with various aldehyde components to synthesise dual-sequence defined oligomers. Thus, the side chains and the backbones of these macromolecules can be varied independently, exhibi

SUBMITTER: Wetzel KS 

PROVIDER: S-EPMC9814518 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature