Incorporation of tetracarboxylate ions into octacalcium phosphate for the development of next-generation biofriendly materials.

ABSTRACT: Octacalcium phosphate (OCP; Ca₈(HPO₄)₂(PO₄)₄ ∙ 5H₂O) is a precursor of hydroxyapatite found in human bones and teeth, and is among the inorganic substances critical for hard tissue formation and regeneration in the human body. OCP has a layered structure and can incorporate carboxylate ions into its interlayers. However, studies involving the incorporation of tetracarboxylic and multivalent (pentavalent and above) carboxylic acids into OCP have not yet been reported. In this study, we investigate the incorporation of pyromellitic acid (1,2,4,5-benzenetetracarboxylic acid), a type of tetracarboxylic acid, into OCP. We established that pyromellitate ions could be incorporated into OCP by a wet chemical method using an acetate

SUBMITTER: Yokoi T 

PROVIDER: S-EPMC9814588 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature