PK_a of the ligand water molecules in the oxygen-evolving Mn₄CaO₅ cluster in photosystem II.

ABSTRACT: Release of the protons from the substrate water molecules is prerequisite for O₂ evolution in photosystem II (PSII). Proton-releasing water molecules with low pK_a values at the catalytic moiety can be the substrate water molecules. In some studies, one of the ligand water molecules, W2, is regarded as OH^-. However, the PSII crystal structure shows neither proton acceptor nor proton-transfer pathway for W2, which is not consistent with the assumption of W2 = OH^-. Here we report the pK_a values of the four ligand water molecules, W1 and W2 at Mn4 and W3 and W4 at Ca²⁺, of the Mn₄CaO₅ cluster. pK_a(W1) ≈ pK_a(W2) << pK_a(W3) ≈ pK_a(W4) in the Mn₄CaO_5</

SUBMITTER: Saito K 

PROVIDER: S-EPMC9814768 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature