Epicardial Fat Volume Is Associated with Endothelial Dysfunction, but not with Coronary Calcification: From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

ABSTRACT:

Background

The increase in epicardial fat volume (EFV) is related to coronary artery disease (CAD), independent of visceral or subcutaneous fat. The mechanism underlying this association is unclear. Coronary artery calcium (CAC) score and endothelial dysfunction are related to coronary events, but whether EFV is related to these markers needs further clarification.

Objectives

To evaluate the association between automatically measured EFV, cardiovascular risk factors, CAC, and endothelial function.

Methods

In 470 participants from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) with measures of EFV, CAC score and endothelial function, we performed multivariable models to evaluate the relation between cardiovascular risk factors and EFV (response variable

SUBMITTER: Martins KPMP 

PROVIDER: S-EPMC9814820 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature