Encapsulation within a coordination cage modulates the reactivity of redox-active dyes.

ABSTRACT: Confining molecules within well-defined nanosized spaces can profoundly alter their physicochemical characteristics. For example, the controlled aggregation of chromophores into discrete oligomers has been shown to tune their optical properties whereas encapsulation of reactive species within molecular hosts can increase their stability. The resazurin/resorufin pair has been widely used for detecting redox processes in biological settings; yet, how tight confinement affects the properties of these two dyes remains to be explored. Here, we show that a flexible Pd^II₆L₄ coordination cage can efficiently encapsulate both resorufin and resazurin in the form of dimers, dramatically modulating their optical properties. Furthermore, binding within the cage signific

SUBMITTER: Yanshyna O 

PROVIDER: S-EPMC9814915 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature