An analysis of organism lifelines in an industrial bioreactor using Lattice-Boltzmann CFD.

ABSTRACT: Euler-Lagrange CFD simulations, where the biotic phase is represented by computational particles (parcels), provide information on environmental gradients inside bioreactors from the microbial perspective. Such information is highly relevant for reactor scale-down and process optimization. One of the major challenges is the computational intensity of CFD simulations, especially when resolution of dynamics in the flowfield is required. Lattice-Boltzmann large-eddy simulations (LB-LES) form a very promising approach for simulating accurate, dynamic flowfields in stirred reactors, at strongly reduced computation times compared to finite volume approaches. In this work, the performance of LB-LES in resolving substrate gradients in large-scale bioreactors is explored, combined with the inclusio

SUBMITTER: Haringa C 

PROVIDER: S-EPMC9815090 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature