Local structural-functional connectivity decoupling of caudate nucleus in infantile esotropia.

ABSTRACT: Abnormal brain structural and functional properties were demonstrated in patients with infantile esotropia (IE). However, few studies have investigated the interaction between structural and functional connectivity (SC-FC) in patients with IE. Structural network was generated with diffusion tensor imaging and functional network was constructed with resting-state functional magnetic resonance imaging for 18 patients with IE as well as 20 age- and gender- matched healthy subjects. The SC-FC coupling for global connectome, short connectome and long connectome were examined in IE patients and compared with those of healthy subjects. A linear mixed effects model was employed to examine the group-age interaction in terms of the coupling metrics. The Pearson correlation between coupling measures

SUBMITTER: Guo J 

PROVIDER: S-EPMC9815444 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature