Synergizing liver systemic treatments with interventional oncology: friend or foe?

ABSTRACT: Interventional radiology techniques provide excellent local tumor control for small tumors in various organs, but several limitations can hamper the oncological outcomes such as the tumor size or the number of lesions. Technical improvements, optimal patient selection and combination with systemic therapies, including immune checkpoint inhibitors, have been successfully developed to overcome these barriers.In this setting, chemotherapy and targeted therapies aim to diminish the tumor burden in addition to local treatments, while immunotherapies may have a synergistic effect in terms of mechanism of action on the tumor cell as well as the immune environment, with multiple treatment combinations being available. Finally, interventional Rrdiology treatments often increase tumor antigen exposu

SUBMITTER: Jost R 

PROVIDER: S-EPMC9815737 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature