Cell types and molecular architecture of the Octopus bimaculoides visual system.

ABSTRACT: Cephalopods have a remarkable visual system, with a camera-type eye and high acuity vision that they use for a wide range of sophisticated visually driven behaviors. However, the cephalopod brain is organized dramatically differently from that of vertebrates and invertebrates, and beyond neuroanatomical descriptions, little is known regarding the cell types and molecular determinants of their visual system organization. Here, we present a comprehensive single-cell molecular atlas of the octopus optic lobe, which is the primary visual processing structure in the cephalopod brain. We combined single-cell RNA sequencing with RNA fluorescence in situ hybridization to both identify putative molecular cell types and determine their anatomical and spatial organization within the optic lobe. Our r

SUBMITTER: Songco-Casey JO 

PROVIDER: S-EPMC9815951 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature