Reproducibility of [18F]FDG PET/CT liver SUV as reference or normalisation factor.

ABSTRACT:

Introduction

Although visual and quantitative assessments of [18F]FDG PET/CT studies typically rely on liver uptake value as a reference or normalisation factor, consensus or consistency in measuring [18F]FDG uptake is lacking. Therefore, we evaluate the variation of several liver standardised uptake value (SUV) measurements in lymphoma [18F]FDG PET/CT studies using different uptake metrics.

Methods

PET/CT scans from 34 lymphoma patients were used to calculate SUVmax^liver, SUVpeak^liver and SUVmean^liver as a function of (1) volume-of-interest (VOI) size, (2) location, (3) imaging time point and (4) as a function of total metabolic tumour volume (MTV). The impact of reconstruction protocol on liver uptake is studied on 15 baseline lymphoma pati

SUBMITTER: Zwezerijnen GJC 

PROVIDER: S-EPMC9816285 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature