Guidance for the treatment of adult growth hormone deficiency with somapacitan, a long-acting growth hormone preparation.

ABSTRACT: Adult growth hormone deficiency (AGHD) is a rare endocrine disorder characterized by an abnormal body composition, metabolic abnormalities associated with increased cardiovascular diseases, bone loss, and impaired quality of life. Daily subcutaneous injections with recombinant growth hormone (GH) can alleviate the abnormalities associated with AGHD. Several long-acting GH (LAGH) preparations are currently in development that aim to reduce treatment burden for patients receiving daily GH injections. Somapacitan (Sogroya^®; Novo Nordisk, Denmark) is the first LAGH preparation that has been approved for treatment of AGHD in the United States, Europe, and Japan. The recent approval of somapacitan and anticipated approval of other LAGH molecules presents new questions for physicians p

SUBMITTER: Bidlingmaier M 

PROVIDER: S-EPMC9816378 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature