Project description:BackgroundIntussusception can occur at any age and is common in children but less common in adults. This study aimed to evaluate our experience of 51 adult intussusception and study the etiology, clinical manifestations, diagnosis, and treatment.MethodsThis analysis assessed the clinical manifestations, etiology, diagnosis, and treatment of adult intussusception in 51 adult patients at the Department of Gastrointestinal Surgery of China-Japan Union Hospital of Jilin University from January 2010 to December 2020.ResultsThe mean age of the cohort was 54.43 ± 18.21 years, and 42 patients were diagnosed by abdominal ultrasonography and abdominal computed tomography (CT). Among them, 76.5% (39/51) had abdominal pain, 11.8% (6/51) had blood in stool, and 5.9% (3/51) had a palpable abdominal mass. Of these, 62.7% had tumors: malignant accounted for 39.2% (20/51) and benign accounted for 23.5% (12/51). CT is the preferred imaging method with a sensitivity of 92.2%, while colonoscopy provides a complementary diagnosis in patients involving the colon. All patients underwent surgical treatment, including 21.6% (11/51) laparoscopic surgery, 74.5% (38/51) open surgery, and 5.9% (3/51) intussusception reduction during the operation. The average operation time of the open group was 133.27 ± 43.75 min and the average hospital stay was 16.24 ± 12.55 days, while the average operation time of the laparoscopic group was 140.50 ± 46.15 mins, and the average hospital stay was 16.60 ± 16.98 days (P > 0.05).ConclusionAdult intussusception is a rare disease in clinic. Laparoscopic surgery can be useful and safe for adult intussusception.

| S-EPMC9744142 | biostudies-literature

Characteristics of Adult Intussusception due to Malignancy in Japanese Patients.

Project description:AimsAdult intussusception (AI) is often associated with organic diseases. However, few studies have examined the causes of AI in Japanese patients. This study aimed to elucidate the clinical characteristics of AI due to malignancy in Japanese patients.Methods and resultsFrom 2013 to 2021, 54 Japanese patients with AI (≥ 20 years) diagnosed at our hospital were enrolled and divided into two groups according to the cause of AI (malignancy group, n = 26; other diseases group, n = 28). The patients' clinical characteristics were retrospectively evaluated. Patients in the malignancy group were significantly older than those in the other diseases group (p < 0.001). The cutoff value for age as a factor associated with AI due to malignancy was 64 years (area under the curve: 0.78, 95% confidence interval [CI]: 0.65-0.90). The frequency of chronic symptoms (> 14 days) in AI due to malignancy was significantly higher than the frequencies of acute (≤ 4 days) and subacute (4-14 days) symptoms (p = 0.010 and p = 0.027, respectively). The colonic type of AI was significantly more common than the small intestinal and ileocecal types in the malignancy group (both p < 0.001). Multivariate analysis showed that age of ≥ 64 years, chronic symptoms, and the colonic type were independently associated with AI due to malignancy (adjusted odds ratio [OR] 16.00, 95% CI 1.23-208.00; adjusted OR 32.70, 95% CI 1.50-712.00; adjusted OR 31.20, 95% CI 2.68-363.00, respectively).ConclusionAdvanced age (≥ 64 years), chronic symptoms, and AI in the colon are characteristics of AI due to malignancy.

| S-EPMC11840692 | biostudies-literature

Adult Small Gut Intussusception Caused by Ascaris as a Lead Point.

Project description: Not available

| S-EPMC4530733 | biostudies-literature

Case report: Submucosal cavernous lymphangioma causing jejuno-jejunal intussusception in an adult.

Project description:Cavernous lymphangioma often occurs in the head, neck, trunk, and extremities of infants and children, and it is rare to cause a small intestine intussusception in adults. In this case, a 32-year-old woman presented with abdominal pain, vomiting, and a 5 cm × 5 cm abdominal mass on the left side of the abdomen. Laboratory tests showed anemia and CT showed small intestinal intussusception. After conservative treatments, her symptoms disappeared. However, 18F-FDG PET/CT suggested malignancy and her symptoms reappeared after eating something. Segmental jejunal resection was performed and pathology showed submucosal cavernous lymphangioma. At the 1-year follow-up, the patient was asymptomatic. Then this paper reviewed the literature on small intestinal cavernous lymphangioma in adults and found that this is the first English case report of intussusception caused by a jejunal submucosal cavernous lymphangioma in an adult. Current problem is that adult intussusception and intestinal lymphangioma are difficult to diagnose preoperatively. Imaging techniques such as tomography and PET/CT aid in the diagnosis of these benign lesions. Surgical resection was considered to be the required treatment and seems to have had no recurrence in adults according to the literature.

| S-EPMC9632977 | biostudies-literature

Adult Ileoileal Intussusception Caused by Diffuse Large B-cell Lymphoma<sup>⋆</sup>.

Project description:Adult intussusception is a rare diagnosis that can be caused by non-Hodgkin's diffuse large B-cell lymphoma (DLBCL). In this case report, we discuss a middle-aged man who presented with non-specific symptoms of intussusception and absence of classic B symptoms. He was found to have intussusception secondary to stage IIIE, CD20 positive DLBCL. The patient underwent small bowel resection with anastomosis, followed by 6 cycles of R-CHOP, which resulted in complete remission of his neoplasm. In reporting this case, we hope to further highlight the role of malignancy in intussusception and guidance on appropriate therapy.

| S-EPMC11000829 | biostudies-literature

Echography-guided Botulinum Toxin for Moving Ear Syndrome.

Project description:BackgroundMoving Ear Syndrome is a rare hyperkinetic disorder.Phenomenology shownThis Video Abstract illustrates typical backward movements of the right ear associated with pain and discomfort in a man with Moving Ear Syndrome.Educational valueMoving Ear Syndrome is effectively and safely treatable with EMG-US-guided botulinum toxin injections.

| S-EPMC11568798 | biostudies-literature

Successful endoscopic management of adult ileocecal intussusception secondary to a large ileal lipoma.

Project description: Not available

| S-EPMC8058388 | biostudies-literature

Transient Descending Colocolonic Intussusception Due to a Large Fecaloma in an Adult.

Project description:Intussusception typically occurs in infants and children, with adults representing 5% of cases. A 53-year-old African American woman presented with lower abdominal pain and tenderness. Computed tomography of the abdomen and pelvis demonstrated a 3.5 cm colocolonic intussusception in the descending colon. Emergent colonoscopy found solid stool in the mid descending colon. Water-soluble rectal enema showed a filling defect in the mid descending colon. Repeat colonoscopy demonstrated presence of a large fecaloma in left colon. Laxatives were initiated, and abdominal pain subsided. To our knowledge, this is the first report of colocolonic intussusception secondary to fecaloma.

| S-EPMC5541757 | biostudies-other

Infantile intussusception.

Project description: Not available

| S-EPMC4427896 | biostudies-literature