Validation of the GALAD model and establishment of a new model for HCC detection in Chinese patients.

ABSTRACT:

Background

GALAD model is a statistical model used to estimate the possibility of hepatocellular carcinoma (HCC) in patients with chronic liver disease. Many studies with other ethnic populations have shown that it has high sensitivity and specificity. However, whether this model can be used for Chinese patients remains to be determined. Our study was conducted to verify the performance of GALAD model in a Chinese cohort and construct a new model that is more appropriately for Chinese populations.

Methods

There are total 512 patients enrolled in the study, which can be divided into training set and validation set. 80 patients with primary liver cancer, 139 patients with chronic liver disease and 87 healthy people were included in the training set. Through the ROC(receiver op

SUBMITTER: Li L 

PROVIDER: S-EPMC9817025 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature