MiRNA regulated therapeutic potential of the stromal vascular fraction: Current clinical applications - A systematic review.

ABSTRACT:

Introduction

The stromal vascular fraction (SVF) is a heterogeneous population of cells that, interacting with each other, can affect the processes of regeneration, angiogenesis, and immunomodulation. Over the past 20 years, there has been a trend towards an increase in the number of clinical studies on the therapeutic use of SVF. MicroRNAs (miRNAs) are also important regulators of cellular function and they have been shown to be involved in SVF cellular component function. The purpose of this study was to analyze existing clinical studies on the therapeutic use of SVF including the role of miRNAs in the regulation of the function of the cellular component of SVF as an anti-inflammatory, pro-angiogenic and cell differentiation activity.

Methods

The search strategy was to use

SUBMITTER: Agaverdiev M 

PROVIDER: S-EPMC9817091 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature