Opioid-Free Anesthesia and Postoperative Outcomes in Cancer Surgery: A Systematic Review.

ABSTRACT:

Background

Surgery is an essential component of the treatment of solid tumors, but the perioperative course can be complicated by different factors (including anesthesia). Opioid-free anesthesia (OFA) may mitigate adverse outcomes of opioid-based anesthesia (OBA), but major questions remain on the actual impact in terms of analgesia and the improvement of surgical outcomes. To address this issue, we present a systematic review to evaluate the efficacy of OFA compared to OBA in the specific subset of cancer patients undergoing surgery.

Methods

following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA), we searched MEDLINE, Embase and the Cochrane CENTRAL Library to include randomized controlled trials (RCTs) on adults undergoing oncological surg

SUBMITTER: Bugada D 

PROVIDER: S-EPMC9817782 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature