Aggression in Group-Housed Male Mice: A Systematic Review.

ABSTRACT: Aggression among group-housed male mice is a major animal welfare concern often observed at animal facilities. Studies designed to understand the causes of male mice aggression have used different methodological approaches and have been heterogeneous, using different strains, environmental enrichments, housing conditions, group formations and durations. By conducting a systematic literature review based on 198 observed conclusions from 90 articles, we showed that the methodological approach used to study aggression was relevant for the outcome and suggested that home cage observations were better when studying home cage aggression than tests provoking aggression outside the home cage. The study further revealed that aggression is a complex problem; one solution will not be appropriate for

SUBMITTER: Weber EM 

PROVIDER: S-EPMC9817818 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature