The Current and Future Promises of Combination Radiation and Immunotherapy for Genitourinary Cancers.

ABSTRACT: As the indications for the use of immunotherapy in genitourinary malignancies expand, its role in combination with standard or conventional therapies has become the subject of contemporary studies. Radiotherapy has multiple immunomodulating effects on anti-tumor immune response, which highlights potential synergistic role with immunotherapy agents. We sought to review the body of published data studying the combination of immunotherapy and radiotherapy as well as the rationale for combination therapy. Trial information and primary articles were obtained using the following terms "immunotherapy", "radiotherapy", "prostate cancer", and "bladder cancer." All articles and trials were screened to ensure they included combination radiotherapy and immunotherapy. The effects of radiation on the im

SUBMITTER: Saidian A 

PROVIDER: S-EPMC9818005 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature