Mesenchymal Stem Cells in Radiation-Induced Pulmonary Fibrosis: Future Prospects.
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ABSTRACT:
SUBMITTER: Chen Y
PROVIDER: S-EPMC9818136 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
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Mesenchymal Stem Cells in Radiation-Induced Pulmonary Fibrosis: Future Prospects.
Chen Yusha Y Liu Xuefeng X Tong Zhaohui Z
Cells 20221220 1
Radiation-induced pulmonary fibrosis (RIPF) is a general and fatal side effect of radiotherapy, while the pathogenesis has not been entirely understood yet. By now, there is still no effective clinical intervention available for treatment of RIPF. Recent studies revealed mesenchymal stromal cells (MSCs) as a promising therapy treatment due to their homing and differentiation ability, paracrine effects, immunomodulatory effects, and MSCs-derived exosomes. Nevertheless, problems and challenges in ...[more]
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