Hepcidin as a Diagnostic Biomarker in Anaemic Lung Cancer Patients.

ABSTRACT: We aim to describe the characteristics of hepcidin, IL-6, and TNF-α levels in anaemia of lung cancer patients with operative tumour as well as to investigate the potential diagnostic capabilities of hepcidin in combination with IL-6, TNF-α, and acute phase proteins. We present a retrospective study of 112 lung cancer patients (41 women and 71 men) who were surgically treated at the Lower Silesian Centre for Lung Diseases in Wroclaw, Poland. Serum blood samples were collected from all these patients prior to any surgical treatment and used to determine hepcidin, IL-6, TNF-α, SAA₁, and CRP concentrations. Patients were also examined with a complete blood count several times during their hospitalization. The female and male groups were divided based on the occurrence of anaemia dur

SUBMITTER: Wadowska K 

PROVIDER: S-EPMC9818260 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature