Interstitial Lung Disease in Immunocompromised Children.

ABSTRACT:

Background

The range of pulmonary complications beyond infections in pediatric immunocompromised patients is broad but not well characterized. Our goal was to assess the spectrum of disorders with a focus on interstitial lung diseases (ILD) in immunodeficient patients.

Methods

We reviewed 217 immunocompromised children attending a specialized pneumology service during a period of 23 years. We assigned molecular diagnoses where possible and categorized the underlying immunological conditions into inborn errors of immunity or secondary immunodeficiencies according to the IUIS and the pulmonary conditions according to the chILD-EU classification system.

Results

Among a wide array of conditions, opportunistic and chronic infections were the most frequent. ILD had a 40% pr

SUBMITTER: Gao X 

PROVIDER: S-EPMC9818431 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature