Essential Role of Multi-Omics Approaches in the Study of Retinal Vascular Diseases.

ABSTRACT: Retinal vascular disease is a highly prevalent vision-threatening ocular disease in the global population; however, its exact mechanism remains unclear. The expansion of omics technologies has revolutionized a new medical research methodology that combines multiple omics data derived from the same patients to generate multi-dimensional and multi-evidence-supported holistic inferences, providing unprecedented opportunities to elucidate the information flow of complex multi-factorial diseases. In this review, we summarize the applications of multi-omics technology to further elucidate the pathogenesis and complex molecular mechanisms underlying retinal vascular diseases. Moreover, we proposed multi-omics-based biomarker and therapeutic strategy discovery methodologies to optimize clinical an

SUBMITTER: Lei Y 

PROVIDER: S-EPMC9818611 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature