Variability in the Response against Teladorsagia circumcincta in Lambs of Two Canarian Sheep Breeds.

ABSTRACT: The increasing resistance to anthelmintics has necessitated the exploration of alternative control strategies of gastrointestinal nematode (GIN) infections. A sustainable option is genetic selection based on differences in susceptibility to GIN infection between and within breeds of sheep. Here, three-month-old Canaria Hair breed (GIN-resistant) and Canaria Sheep breed (GIN-susceptible) showed no significant between-breed differences after trickle infection with Teladorsagia circumcincta, whereas considerable individual variability was found in both breeds. Next, data from lambs of both breeds were used to explore the relationships between parasitological variables and T. circumcincta-specific IgA levels, local immune cell populations, and abomasal lymph node gene expression

SUBMITTER: Perez-Hernandez T 

PROVIDER: S-EPMC9820046 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature