MicroRNAs in T Cell-Immunotherapy.
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ABSTRACT:
SUBMITTER: Dosil SG
PROVIDER: S-EPMC9820302 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Publications
MicroRNAs in T Cell-Immunotherapy.
Dosil Sara G SG Rodríguez-Galán Ana A Sánchez-Madrid Francisco F Fernández-Messina Lola L
International journal of molecular sciences 20221223 1
MicroRNAs (miRNAs) act as master regulators of gene expression in homeostasis and disease. Despite the rapidly growing body of evidence on the theranostic potential of restoring miRNA levels in pre-clinical models, the translation into clinics remains limited. Here, we review the current knowledge of miRNAs as T-cell targeting immunotherapeutic tools, and we offer an overview of the recent advances in miRNA delivery strategies, clinical trials and future perspectives in RNA interference technolo ...[more]
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