The Role of Staphylococcus aureus and Its Toxins in the Pathogenesis of Allergic Asthma.

ABSTRACT: Bronchial asthma is one of the most common chronic diseases worldwide and affects more than 300 million patients. Allergic asthma affects the majority of asthmatic children as well as approximately 50% of adult asthmatics. It is characterized by a Th2-mediated immune response against aeroallergens. Many aspects of the overall pathophysiology are known, while the underlying mechanisms and predisposing factors remain largely elusive today. Over the last decade, respiratory colonization with Staphylococcus aureus (S. aureus), a Gram-positive facultative bacterial pathogen, came into focus as a risk factor for the development of atopic respiratory diseases. More than 30% of the world’s population is constantly colonized with S. aureus in their nasopharynx. This colonization is mostly asymptoma

SUBMITTER: Jorde I 

PROVIDER: S-EPMC9820472 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature