Ontology highlight
ABSTRACT:
SUBMITTER: Silva BF
PROVIDER: S-EPMC9820800 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Silva Bruna F BF Corrêa Graciely G GG Zocca Vitória F B VFB Picheli Flavio P FP Lins Milca R C R MRCR Pedrolli Danielle B DB
International journal of molecular sciences 20221221 1
Autonomous control of gene expression through engineered quorum-sensing processes is broadly applicable to biosynthetic pathways, including simultaneous control of different genes. It is also a powerful tool for balancing growth and production. We had previously engineered a modular autoinduction device for the control of gene expression in <i>B. subtilis</i>. Now, we expand its functionality to repress gene expression autonomously. The engineered R8 promoter responds to AHL accumulation in the ...[more]