RPS24 Is Associated with a Poor Prognosis and Immune Infiltration in Hepatocellular Carcinoma.

ABSTRACT: Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy, with increased mortality and morbidity. Accumulating evidence suggested that 40S ribosomal protein S24 (RPS24) is related to malignant outcomes and progression. However, the role of RPS24 remains unclear in HCC. The mRNA and protein expression pattern of RPS24 in HCC was explored and confirmed based on the bioinformatics analysis and histological examination. The correlation between RPS24 expression and clinicopathological features, diagnostic value, prognosis, methylation status, and survival were evaluated. Then, we divided the HCC cohort into two groups based on the expression of RPS24, and performed the functional enrichment and immune cells infiltration analysis of RPS24. Furthermore, in vivo and in vi

SUBMITTER: Li H 

PROVIDER: S-EPMC9820840 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature