Genomics and Epigenomics in the Molecular Biology of Melanoma-A Prerequisite for Biomarkers Studies.
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ABSTRACT:
SUBMITTER: Zob DL
PROVIDER: S-EPMC9821083 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Publications
Genomics and Epigenomics in the Molecular Biology of Melanoma-A Prerequisite for Biomarkers Studies.
Zob Daniela Luminita DL Augustin Iolanda I Caba Lavinia L Panzaru Monica-Cristina MC Popa Setalia S Popa Alina Delia AD Florea Laura L Gorduza Eusebiu Vlad EV
International journal of molecular sciences 20221231 1
Melanoma is a common and aggressive tumor originating from melanocytes. The increasing incidence of cutaneous melanoma in recent last decades highlights the need for predictive biomarkers studies. Melanoma development is a complex process, involving the interplay of genetic, epigenetic, and environmental factors. Genetic aberrations include <i>BRAF</i>, <i>NRAS</i>, <i>NF1</i>, <i>MAP2K1/MAP2K2</i>, <i>KIT</i>, <i>GNAQ</i>, <i>GNA11</i>, <i>CDKN2A</i>, <i>TERT</i> mutations, and translocations o ...[more]
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