Innate Immunity in Cardiovascular Diseases-Identification of Novel Molecular Players and Targets.

ABSTRACT: During the past few years, unexpected developments have driven studies in the field of clinical immunology. One driver of immense impact was the outbreak of a pandemic caused by the novel virus SARS-CoV-2. Excellent recent reviews address diverse aspects of immunological re-search into cardiovascular diseases. Here, we specifically focus on selected studies taking advantage of advanced state-of-the-art molecular genetic methods ranging from genome-wide epi/transcriptome mapping and variant scanning to optogenetics and chemogenetics. First, we discuss the emerging clinical relevance of advanced diagnostics for cardiovascular diseases, including those associated with COVID-19-with a focus on the role of inflammation in cardiomyopathies and arrhythmias. Second, we consider newly identified im

SUBMITTER: Poller W 

PROVIDER: S-EPMC9821340 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature