Fluorescence lifetime distribution in phakic and pseudophakic healthy eyes.

ABSTRACT:

Purpose

To investigate the influence of the lens status and to describe fundus autofluorescence lifetimes (FLT) in a large cohort of healthy eyes across a wide age range.

Materials and methods

FLT data were acquired from healthy phakic and pseudophakic eyes using fluorescence lifetime imaging ophthalmoscopy (FLIO). Retinal autofluorescence was excited with a 473 nm laser and emitted autofluorescence was detected in a short and a long spectral channel (SSC: 498-560 nm; LSC: 560-720 nm).

Results

141 healthy eyes from 141 participants (56 ± 18 years) were included. The shortest mean FLTs were measured within the macular center, followed by the temporal inner and outer ETDRS (Early Treatment Diabetic Retinopathy Study) grid segments, and the remaining areas of the inner a

SUBMITTER: Dysli C 

PROVIDER: S-EPMC9821472 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature