Adiponectin and Interleukin-33: Possible Early Markers of Metabolic Syndrome.

ABSTRACT: Adiponectin is one of the most important molecules in the body's compensatory response to the development of insulin resistance. By trying to maintain insulin sensitivity, increase insulin secretion and prevent inflammation, adiponectin tries to maintain glucose homeostasis. Interleukin-33, which belongs to the group of alarmins, also promotes insulin secretion. Interleukin-33 might be either pro-inflammatory or anti-inflammatory depending on the disease and the model. However, interleukin-33 has shown various protective effects in CVD, obesity and diabetes. The aim of our study was to investigate the association between adiponectin and interleukin-33 in patients with metabolic syndrome. As expected, all patients with metabolic syndrome had worse parameters that represent the hallmark of m

SUBMITTER: Nesic J 

PROVIDER: S-EPMC9821697 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature