GC-MS and LC-DAD-MS Phytochemical Profiling for Characterization of Three Native Salvia Taxa from Eastern Mediterranean with Antiglycation Properties

ABSTRACT: Salvia fruticosa and S. pomifera subsp. calycina are native to Eastern Mediterranean and S. pomifera subsp. pomifera is endemic to Greece. The primary aim of this study was to develop an analytical methodology for metabolomic profiling and to study their efficacy in combating glycation, the major biochemical complication of diabetes. After sequential ultrasound-assisted extraction of 2 g of leaves with petroleum ether and 70% methanol, the volatile metabolites in the petroleum ether extracts were studied with GC-MS (Gas Chromatography-Mass Spectrometry), whereas the polar metabolites in the hydroalcoholic extracts were determined and quantified by UHPLC-DAD–ESI-MS (Ultra-High Performance Liquid Chromatography–Diode Array Detector–Mass Spectrometry). This methodology was applied to five pop

SUBMITTER: Gkioni M 

PROVIDER: S-EPMC9821822 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature