Prognostic significance of microinvasion with ductal carcinoma in situ of the breast: a meta-analysis.

ABSTRACT:

Purpose

Ductal carcinoma in situ (DCIS) associated with invasive carcinoma ≤ 1 mm in size is defined as DCIS with microinvasion (DCIS/microinvasion) rather than as invasive breast carcinoma. The number of patients with microinvasion accounts for < 1% of all breast cancer in published studies. As the numbers are limited, the prognostic significance of DCIS/microinvasion has not been clearly elucidated. This meta-analysis aimed to investigate the survival differences between patients with DCIS/microinvasion and those with pure DCIS.

Methods

A meta-analysis following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology was performed. We searched three electronic databases (MEDLINE, Cochrane Library, and EMBASE) and included observational s

SUBMITTER: Shiino S 

PROVIDER: S-EPMC9823049 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature