Genetic and Environmental Variation in Continuous Phenotypes in the ABCD Study®.

ABSTRACT: Twin studies yield valuable insights into the sources of variation, covariation and causation in human traits. The ABCD Study® (abcdstudy.org) was designed to take advantage of four universities known for their twin research, neuroimaging, population-based sampling, and expertise in genetic epidemiology so that representative twin studies could be performed. In this paper we use the twin data to: (i) provide initial estimates of heritability for the wide range of phenotypes assessed in the ABCD Study using a consistent direct variance estimation approach, assuring that both data and methodology are sound; and (ii) provide an online resource for researchers that can serve as a reference point for future behavior genetic studies of this publicly available dataset. Data were analyzed from 772

SUBMITTER: Maes HHM 

PROVIDER: S-EPMC9823057 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature